phospholipase c in beijing strains of mycobacterium tuberculosis

Phospholipase C in Beijing strains of Mycobacterium tuberculosis

BACKGROUND AND OBJECTIVES Phospholipase of Mycobacterium tuberculosis plays an important role in pathogenesis through breaking up phospholipids and production of diacylglycerol. In this study, we examined the Beijing strains of Mycobacterium tuberculosis isolated from Iranian patients for the genes encoding this enzyme. MATERIALS AND METHODS DNA extraction was performed using CTAB (cetyltrime...

بررسی رابطه ژن‌های فسفولیپاز C با پاتوژنیسیته مایکوباکتریوم توبرکلوزیس سویه بیجینگ وسویه غیربیجینگ

Abstract Background: The Beijing strain of Mycobacterium tuberculosis is responsible for more than 25% of cases of Tuberculosis in the world, it has a high transmission potential and there is a significant correlation between Beijing strain and multidrug resistance. In this study we compared the presence of Phospholipase C genes in Beijing and Nonbeijing strains of Mycobacterium tuberculosis...

Prevalence of Mycobacterium tuberculosis Beijing strains in Punjab Pakistan

Beijing strains possess unique properties such as, multi-drug resistance, evasion of BCG vaccination and disseminating at a greater rate than nonBeijing strains. Various methods exist for the detection of Beijing strains such as, RFLP or spoligotyping; however, these methods require established cultures and DNA isolated in High concentration. Relatively newer methods such as, MIRU VNTR, are mor...

Non-Beijing strains of Mycobacterium tuberculosis in China.

In a 2-year prospective study of tuberculosis (TB) patients in China, the prevalences of non-Beijing strains of Mycobacterium tuberculosis varied between Shandong Province (20.6%), Shanghai (27.6%), and Sichuan Province (45.9%) (P < 0.005). These differences may be due to factors such as human migration, transmission, or diversification and adaptation of the mycobacteria to different hosts.

Transmission of Mycobacterium tuberculosis Beijing Strains , Alberta , Canada , 1991 – 2007

Transmission of Mycobacterium tuberculosis Beijing Strains, Alberta, Canada, 1991–2007

Beijing strains are speculated to have a selective advantage over other Mycobacterium tuberculosis strains because of increased transmissibility and virulence. In Alberta, a province of Canada that receives a large number of immigrants, we conducted a population-based study to determine whether Beijing strains were associated with increased transmission leading to disease compared with non-Beij...